| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| guaA1 | infC | sce3679 | sce4486 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | 0.446 |
| guaA1 | pnpA | sce3679 | sce4541 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Polynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.864 |
| guaA1 | rplA | sce3679 | sce0407 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.913 |
| guaA1 | rpmI | sce3679 | sce7246 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L35; High confidence in function and specificity; Belongs to the bacterial ribosomal protein bL35 family. | 0.474 |
| guaA1 | rpoB | sce3679 | sce0410 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.905 |
| guaA1 | rpsI | sce3679 | sce7404 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 30S ribosomal protein S9; High confidence in function and specificity; Belongs to the universal ribosomal protein uS9 family. | 0.604 |
| guaA1 | sce0926 | sce3679 | sce0926 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | GTP-binding protein; Family membership. | 0.791 |
| guaA1 | tig | sce3679 | sce3146 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.763 |
| guaA1 | tsf | sce3679 | sce3133 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Elongation factor EF-Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.746 |
| infC | guaA1 | sce4486 | sce3679 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.446 |
| infC | pnpA | sce4486 | sce4541 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | Polynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.512 |
| infC | rplA | sce4486 | sce0407 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.924 |
| infC | rpmI | sce4486 | sce7246 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | 50S ribosomal protein L35; High confidence in function and specificity; Belongs to the bacterial ribosomal protein bL35 family. | 0.933 |
| infC | rpoB | sce4486 | sce0410 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.740 |
| infC | rpsI | sce4486 | sce7404 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | 30S ribosomal protein S9; High confidence in function and specificity; Belongs to the universal ribosomal protein uS9 family. | 0.953 |
| infC | sce0926 | sce4486 | sce0926 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | GTP-binding protein; Family membership. | 0.662 |
| infC | tig | sce4486 | sce3146 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.804 |
| infC | tsf | sce4486 | sce3133 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | Elongation factor EF-Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.933 |
| pnpA | guaA1 | sce4541 | sce3679 | Polynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.864 |
| pnpA | infC | sce4541 | sce4486 | Polynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | 0.512 |
