Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (313 aa)    
Predicted Functional Partners:
sce0357
Hypothetical protein predicted by Glimmer/Critica; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.992
sce1736
Citrate synthase (EC 2.3.3.1).
  
 0.991
cis1
Citrate synthase; Family membership; Belongs to the citrate synthase family.
  
 0.988
cis2
Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family.
  
 0.988
fumC1
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.975
fumC2
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.975
maeB1
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); High confidence in function and specificity.
  
 0.955
maeB2
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); Family membership.
  
 0.955
aceB
Malate synthase; High confidence in function and specificity; Belongs to the malate synthase family.
   
 0.927
aspB1
Aspartate transaminase; Family membership.
  
 0.919
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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