| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gcvH | lipA | sce2013 | sce1573 | Glycine cleavage system protein H homologue; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.968 |
| gcvH | sce1072 | sce2013 | sce1072 | Glycine cleavage system protein H homologue; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | nifU domain protein. | 0.649 |
| iscU | nifS | sce7330 | sce3703 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Cysteine desulfurase; High confidence in function and specificity. | 0.996 |
| iscU | sce1072 | sce7330 | sce1072 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | nifU domain protein. | 0.848 |
| iscU | sce5870 | sce7330 | sce5870 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Hypothetical protein; Belongs to the HesB/IscA family. | 0.859 |
| iscU | sce6471 | sce7330 | sce6471 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Glutaredoxin-like protein. | 0.916 |
| iscU | sce7331 | sce7330 | sce7331 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Hypothetical protein; Belongs to the HesB/IscA family. | 0.976 |
| iscU | sdhB1 | sce7330 | sce6555 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Succinate dehydrogenase; High confidence in function and specificity. | 0.532 |
| iscU | sdhB2 | sce7330 | sce8309 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Succinate dehydrogenase; High confidence in function and specificity. | 0.532 |
| iscU | yfhO | sce7330 | sce7329 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.999 |
| lipA | gcvH | sce1573 | sce2013 | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Glycine cleavage system protein H homologue; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.968 |
| lipA | sce1072 | sce1573 | sce1072 | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | nifU domain protein. | 0.889 |
| lipA | sce6471 | sce1573 | sce6471 | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Glutaredoxin-like protein. | 0.500 |
| nifS | iscU | sce3703 | sce7330 | Cysteine desulfurase; High confidence in function and specificity. | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.996 |
| nifS | sce1072 | sce3703 | sce1072 | Cysteine desulfurase; High confidence in function and specificity. | nifU domain protein. | 0.735 |
| nifS | sce5870 | sce3703 | sce5870 | Cysteine desulfurase; High confidence in function and specificity. | Hypothetical protein; Belongs to the HesB/IscA family. | 0.782 |
| nifS | sce6471 | sce3703 | sce6471 | Cysteine desulfurase; High confidence in function and specificity. | Glutaredoxin-like protein. | 0.845 |
| nifS | sce7331 | sce3703 | sce7331 | Cysteine desulfurase; High confidence in function and specificity. | Hypothetical protein; Belongs to the HesB/IscA family. | 0.906 |
| nifS | yfhO | sce3703 | sce7329 | Cysteine desulfurase; High confidence in function and specificity. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.916 |
| sce1072 | gcvH | sce1072 | sce2013 | nifU domain protein. | Glycine cleavage system protein H homologue; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.649 |