trpB protein (Sorangium cellulosum So ce56) - STRING interaction network

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trpB

Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (378 aa)

Predicted Functional Partners:

trpC

0.999

trpA

0.999

trpD

0.994

pabB

0.983

trpE

0.970

sce0620

0.952

serB

0.935

glyA

0.925

sce0438

0.911

cysB

0.911

Your Current Organism:

Sorangium cellulosum So ce56

NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cysB	glyA	sce8782	sce6587	Cystathionine beta-synthase; High confidence in function and specificity.	Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.943
cysB	sce0438	sce8782	sce0438	Cystathionine beta-synthase; High confidence in function and specificity.	Cystathionine beta-synthase; High confidence in function and specificity.	0.915
cysB	serB	sce8782	sce0663	Cystathionine beta-synthase; High confidence in function and specificity.	SerB protein; High confidence in function and specificity.	0.934
cysB	trpA	sce8782	sce1103	Cystathionine beta-synthase; High confidence in function and specificity.	Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.923
cysB	trpB	sce8782	sce1102	Cystathionine beta-synthase; High confidence in function and specificity.	Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.911
cysB	trpC	sce8782	sce1101	Cystathionine beta-synthase; High confidence in function and specificity.	Indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase; High confidence in function and specificity; Belongs to the TrpC family.	0.455
glyA	cysB	sce6587	sce8782	Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Cystathionine beta-synthase; High confidence in function and specificity.	0.943
glyA	pabB	sce6587	sce5043	Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Para-aminobenzoate synthase; High confidence in function and specificity.	0.492
glyA	sce0438	sce6587	sce0438	Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Cystathionine beta-synthase; High confidence in function and specificity.	0.943
glyA	serB	sce6587	sce0663	Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	SerB protein; High confidence in function and specificity.	0.943
glyA	trpA	sce6587	sce1103	Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.930
glyA	trpB	sce6587	sce1102	Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.925
glyA	trpE	sce6587	sce5044	Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Anthranilate synthase; High confidence in function and specificity.	0.492
pabB	glyA	sce5043	sce6587	Para-aminobenzoate synthase; High confidence in function and specificity.	Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.492
pabB	sce0620	sce5043	sce0620	Para-aminobenzoate synthase; High confidence in function and specificity.	Probable anthranilate synthase component I; Family membership.	0.994
pabB	trpA	sce5043	sce1103	Para-aminobenzoate synthase; High confidence in function and specificity.	Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.986
pabB	trpB	sce5043	sce1102	Para-aminobenzoate synthase; High confidence in function and specificity.	Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.983
pabB	trpC	sce5043	sce1101	Para-aminobenzoate synthase; High confidence in function and specificity.	Indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase; High confidence in function and specificity; Belongs to the TrpC family.	0.999
pabB	trpD	sce5043	sce1100	Para-aminobenzoate synthase; High confidence in function and specificity.	Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	0.999
pabB	trpE	sce5043	sce5044	Para-aminobenzoate synthase; High confidence in function and specificity.	Anthranilate synthase; High confidence in function and specificity.	0.999

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