Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
dnaE1DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1108 aa)    
Predicted Functional Partners:
sce1740
Hypothetical protein predicted by Glimmer/Critica.
 
  
 0.979
holA
Putative DNA polymerase III, delta subunit; Family membership.
  
 
 0.854
dnaN
DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.837
dnaX
DNA polymerase III subunit Tau; High confidence in function and specificity.
  
 
 0.800
holB
DNA polymerase III delta' subunit.
  
 
 0.800
sce1712
Exonuclease.
    
 
 0.787
sce7572
DNA polymerase III, epsilon subunit; Specificity unclear.
    
 
 0.787
sce1739
recA recombinase homolog; Family membership.
     
 0.779
ssb
ssDNA-binding protein; High confidence in function and specificity.
   
 
 0.754
sce2627
Single-strand binding protein; High confidence in function and specificity.
   
 
 0.754
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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