Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pheA1PheA1 protein; Family membership. (364 aa)    
Predicted Functional Partners:
aroC
5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.980
trpE
Anthranilate synthase; High confidence in function and specificity.
  
 
 0.957
sce0620
Probable anthranilate synthase component I; Family membership.
 
 
 0.955
hisC2
Histidinol-phosphate aminotransferase; Family membership; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
 
 0.951
pheA3
Chorismate mutase; High confidence in function and specificity.
 
 
0.951
hisC3
Histidinol-phosphate transaminase; Family membership; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
 
 0.949
hisC1
Histidinol-phosphate aminotransferase; Family membership.
 
 
 0.945
hisC4
Histidinol-phosphate transaminase; High confidence in function and specificity; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
 
 0.945
phhA
Phenylalanine 4-monooxygenase; Family membership.
  
  
 0.939
pheA2
P-protein (prephenate dehydratase / chorismate mutase); Family membership.
 
 
0.936
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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