| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroC | hisC1 | sce4843 | sce2262 | 5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Histidinol-phosphate aminotransferase; Family membership. | 0.704 |
| aroC | hisC2 | sce4843 | sce4215 | 5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Histidinol-phosphate aminotransferase; Family membership; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.636 |
| aroC | hisC3 | sce4843 | sce8855 | 5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Histidinol-phosphate transaminase; Family membership; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.636 |
| aroC | hisC4 | sce4843 | sce8915 | 5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Histidinol-phosphate transaminase; High confidence in function and specificity; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.684 |
| aroC | pheA1 | sce4843 | sce1746 | 5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | PheA1 protein; Family membership. | 0.980 |
| aroC | pheA2 | sce4843 | sce7043 | 5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | P-protein (prephenate dehydratase / chorismate mutase); Family membership. | 0.934 |
| aroC | pheA3 | sce4843 | sce7831 | 5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Chorismate mutase; High confidence in function and specificity. | 0.980 |
| aroC | sce0620 | sce4843 | sce0620 | 5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Probable anthranilate synthase component I; Family membership. | 0.949 |
| aroC | trpE | sce4843 | sce5044 | 5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase; High confidence in function and specificity. | 0.969 |
| hisC1 | aroC | sce2262 | sce4843 | Histidinol-phosphate aminotransferase; Family membership. | 5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.704 |
| hisC1 | hisC2 | sce2262 | sce4215 | Histidinol-phosphate aminotransferase; Family membership. | Histidinol-phosphate aminotransferase; Family membership; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.852 |
| hisC1 | hisC3 | sce2262 | sce8855 | Histidinol-phosphate aminotransferase; Family membership. | Histidinol-phosphate transaminase; Family membership; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.857 |
| hisC1 | hisC4 | sce2262 | sce8915 | Histidinol-phosphate aminotransferase; Family membership. | Histidinol-phosphate transaminase; High confidence in function and specificity; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.853 |
| hisC1 | pheA1 | sce2262 | sce1746 | Histidinol-phosphate aminotransferase; Family membership. | PheA1 protein; Family membership. | 0.945 |
| hisC1 | pheA2 | sce2262 | sce7043 | Histidinol-phosphate aminotransferase; Family membership. | P-protein (prephenate dehydratase / chorismate mutase); Family membership. | 0.924 |
| hisC1 | pheA3 | sce2262 | sce7831 | Histidinol-phosphate aminotransferase; Family membership. | Chorismate mutase; High confidence in function and specificity. | 0.946 |
| hisC1 | phhA | sce2262 | sce5266 | Histidinol-phosphate aminotransferase; Family membership. | Phenylalanine 4-monooxygenase; Family membership. | 0.915 |
| hisC1 | trpE | sce2262 | sce5044 | Histidinol-phosphate aminotransferase; Family membership. | Anthranilate synthase; High confidence in function and specificity. | 0.481 |
| hisC2 | aroC | sce4215 | sce4843 | Histidinol-phosphate aminotransferase; Family membership; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.636 |
| hisC2 | hisC1 | sce4215 | sce2262 | Histidinol-phosphate aminotransferase; Family membership; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Histidinol-phosphate aminotransferase; Family membership. | 0.852 |