Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
panE22-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (326 aa)    
Predicted Functional Partners:
panE4
2-dehydropantoate 2-reductase.
  
  
  0.975
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.924
panE3
Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
  
 
0.922
panC
Putative Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.919
panE1
2-dehydropantoate 2-reductase; Family membership.
  
  
  0.916
sce9123
Putative oxidoreductase.
  
  
 
0.913
sce6443
Putative oxidoreductase; Family membership.
     
  0.900
sce7851
Conserved hypothetical enzyme; Family membership; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
   
    0.537
sce2210
Putative pyrazinamidase/nicotinamidase.
   
    0.535
sce5712
Fe2OG dioxygenase domain-containing protein; Unnamed protein product; High confidence in function and specificity.
   
    0.535
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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