STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sce2004Dihydrolipoyl dehydrogenase; Family membership. (465 aa)    
Predicted Functional Partners:
aceF1
Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.957
sucA
Oxoglutarate dehydrogenase (succinyl-transferring); High confidence in function and specificity.
 
 0.949
pdhB1
Pyruvate dehydrogenase (acetyl-transferring); High confidence in function and specificity.
 
 0.940
pdhC
Dihydrolipoyllysine-residue acetyltransferase; High confidence in function and specificity.
 
 0.938
aceF2
Dihydrolipoyllysine-residue acetyltransferase; Family membership.
 
 0.934
pdhB2
Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.932
mazG
Hypothetical protein; Family membership.
 
  
 0.930
nadE-2
Putative NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.913
sce8277
Probable Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.908
cobB
Transcriptional regulatory protein, Sir2 family; Belongs to the sirtuin family. Class III subfamily.
   
 0.905
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.