Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sce2024Hydroxysteroid (17-beta) dehydrogenase 4. (282 aa)    
Predicted Functional Partners:
sce2893
Putative short-chain dehydrogenases; Family membership; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 0.972
sce2001
Putative 3-oxoacyl-[acyl-carrier-protein] reductase.
 
 0.918
sce3815
Short-chain dehydrogenase/reductase; Family membership.
 
 0.918
fabG7
3-oxoacyl-[acyl-carrier protein] reductase; High confidence in function and specificity.
 
 0.868
katE
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
 0.815
sce1998
Enoyl-CoA hydratase.
  
 0.788
sce3179
Putative polyketide biosynthesis enoyl-coa hydratase; Family membership; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.788
sce8810
Oxidoreductase, short-chain dehydrogenase/reductase family; High confidence in function and specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
    
 0.759
sce4164
Hypothetical protein; Acyl-CoA dehydrogenases.
 
 0.685
sce0600
Putative hydroxylase.
 
 0.663
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
Server load: low (38%) [HD]