Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sce2324Dihydrolipoyl dehydrogenase; Family membership. (466 aa)    
Predicted Functional Partners:
aceF1
Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.963
pdhC
Dihydrolipoyllysine-residue acetyltransferase; High confidence in function and specificity.
 
 0.952
pdhB1
Pyruvate dehydrogenase (acetyl-transferring); High confidence in function and specificity.
 
 0.952
aceF2
Dihydrolipoyllysine-residue acetyltransferase; Family membership.
 
 0.949
pdhB2
Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.946
sucA
Oxoglutarate dehydrogenase (succinyl-transferring); High confidence in function and specificity.
  
 0.941
sce8001
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring).
 
 
 0.833
pdhA
Pyruvate dehydrogenase (acetyl-transferring); High confidence in function and specificity.
 
 
 0.825
aceE
Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.809
gcvH
Glycine cleavage system protein H homologue; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.785
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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