Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
treZMalto-oligosyltrehalose trehalohydrolase; High confidence in function and specificity. (614 aa)    
Predicted Functional Partners:
treY
Malto-oligosyltrehalose synthase; High confidence in function and specificity.
 
 0.999
treS
Trehalose synthase; High confidence in function and specificity.
 
 
0.983
otsA
Alpha,alpha-trehalose-phosphate synthase (UDP-forming); High confidence in function and specificity.
  
 0.956
sce3268
Alpha,alpha-trehalose-phosphate synthase (UDP-forming); Family membership.
  
 0.956
otsB
Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
 0.945
sce7170
Alpha-amylase-family protein; Family membership.
  
  
 
0.908
glgP
Phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 
 0.844
sce1303
Glycogen operon protein; Family membership; Belongs to the glycosyl hydrolase 13 family.
 
  
0.840
sce2378
Glycogen debranching enzyme; Family membership; Belongs to the glycosyl hydrolase 13 family.
 
  
0.840
glgC2
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
  
 0.837
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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