Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sce2435Putative sensor kinase; Family membership. (341 aa)    
Predicted Functional Partners:
phoB
Phosphate regulon transcriptional regulatory protein phoB; High confidence in function and specificity.
 
  0.980
sce5073
DNA-binding response regulator; Family membership.
 
  0.979
sce7574
Two-component system response regulator; Family membership.
  
  0.979
sce2434
Two-component response regulator; Family membership.
   0.936
sce8433
Two-component response regulator; Family membership.
 
 
   0.853
sce7217
Unnamed protein product; Family membership.
 
 
 0.842
sce6353
Response regulator; Family membership.
 
   0.812
sce3988
Unnamed protein product; Family membership.
 
   0.811
sce4878
Two-component response regulator; Family membership.
 
   0.810
sce0429
Two-component response regulator; Family membership.
  
   0.806
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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