| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fba1 | fba2 | sce1923 | sce2579 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Fructose-bisphosphate aldolase; Family membership. | 0.928 |
| fba1 | fbp2 | sce1923 | sce2578 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Fructose-bisphosphatase; High confidence in function and specificity. | 0.949 |
| fba1 | gap | sce1923 | sce7350 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); High confidence in function and specificity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.989 |
| fba1 | pfp | sce1923 | sce2257 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Diphosphate-fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. | 0.946 |
| fba1 | sce3599 | sce1923 | sce3599 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Probable Transaldolase; Family membership. | 0.950 |
| fba1 | tal1 | sce1923 | sce1460 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.951 |
| fba1 | tal2 | sce1923 | sce0029 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Probable transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.951 |
| fba1 | tkt1 | sce1923 | sce3987 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.961 |
| fba1 | tkt2 | sce1923 | sce8467 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Tkt2 protein; High confidence in function and specificity. | 0.961 |
| fba1 | tpi | sce1923 | sce7348 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.988 |
| fba2 | fba1 | sce2579 | sce1923 | Fructose-bisphosphate aldolase; Family membership. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.928 |
| fba2 | fbp2 | sce2579 | sce2578 | Fructose-bisphosphate aldolase; Family membership. | Fructose-bisphosphatase; High confidence in function and specificity. | 0.955 |
| fba2 | gap | sce2579 | sce7350 | Fructose-bisphosphate aldolase; Family membership. | Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); High confidence in function and specificity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.935 |
| fba2 | pfp | sce2579 | sce2257 | Fructose-bisphosphate aldolase; Family membership. | Diphosphate-fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. | 0.923 |
| fba2 | sce3599 | sce2579 | sce3599 | Fructose-bisphosphate aldolase; Family membership. | Probable Transaldolase; Family membership. | 0.925 |
| fba2 | tal1 | sce2579 | sce1460 | Fructose-bisphosphate aldolase; Family membership. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.954 |
| fba2 | tal2 | sce2579 | sce0029 | Fructose-bisphosphate aldolase; Family membership. | Probable transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.954 |
| fba2 | tkt1 | sce2579 | sce3987 | Fructose-bisphosphate aldolase; Family membership. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.946 |
| fba2 | tkt2 | sce2579 | sce8467 | Fructose-bisphosphate aldolase; Family membership. | Tkt2 protein; High confidence in function and specificity. | 0.946 |
| fba2 | tpi | sce2579 | sce7348 | Fructose-bisphosphate aldolase; Family membership. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.935 |