Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cumBPutative zinc-binding hydrolase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (177 aa)    
Predicted Functional Partners:
glxK
GlxK protein; High confidence in function and specificity; Belongs to the glycerate kinase type-1 family.
 
 
    0.901
hisIE
Histidine biosynthesis bifunctional protein HisIE; Family membership; In the N-terminal section; belongs to the PRA-CH family.
   
  
 0.881
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
 
 
 0.789
birA
Biotin-(acetyl-CoA-carboxylase) ligase; Family membership.
 
    0.598
adh2
Class III alcohol dehydrogenase; High confidence in function and specificity; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
    0.555
phoH2
PhoH family protein; Family membership.
  
     0.531
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
 
  
 0.528
sun
Sun protein; Family membership; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
   
 0.522
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
  
 0.509
cafA
Ribonuclease G; Family membership.
  
     0.503
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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