Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
kuHypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (320 aa)    
Predicted Functional Partners:
sce3523
DNA_LIGASE_A3 domain-containing protein; Unnamed protein product; High confidence in function and specificity.
 
  
 0.979
ligB
DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
 
  
 0.852
topI
DNA topoisomerase, type I, putative; High confidence in function and specificity.
 
    0.653
sce2663
Hypothetical protein predicted by Glimmer/Critica.
       0.570
sce1115
Predicted membrane protein.
 
     0.568
sce2665
Isochorismatase; Family membership.
       0.486
sce5733
Hypothetical protein.
 
    0.482
sce0289
Putative Oxidoreductase.
  
     0.419
katE
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
 
    0.405
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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