Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
tlpAThiol:disulfide interchange protein tlpA; Family membership. (192 aa)    
Predicted Functional Partners:
msrA2
Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.943
sce4758
Thiol:disulfide interchange protein.
  
 
 0.812
dsbD
Thiol:disulfide interchange protein DsbD.
  
 
 0.812
sce4523
Cytochrome-c oxidase; Family membership.
    
 
 0.801
czcB1
Heavy metal efflux pump, CzcB family; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
   
   0.785
czcA1
Cobalt/zinc/cadmium efflux RND transporter,permease protein, CzcA family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.773
sce8183
Putative secreted disulfide isomerase.
 
   
 0.772
sce2858
ahpC/TSA family protein.
 
   
 0.770
sce2735
Hypothetical protein predicted by Glimmer/Critica.
   
   0.768
sce7592
Putative Cytochrome-c oxidase; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
  
 
 0.759
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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