Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sce2754Fumarate reductase/succinate dehydrogenase flavoprotein; High confidence in function and specificity. (577 aa)    
Predicted Functional Partners:
sdhC2
Succinate dehydrogenase; High confidence in function and specificity.
  
 0.965
fdxE
Putative ferredoxin; Family membership.
 
 
 0.961
sce2756
Hypothetical protein; Phycocyanin alpha-subunit phycocyanobilin lyase and related proteins.
    0.953
sce0357
Hypothetical protein predicted by Glimmer/Critica; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.948
sdhB1
Succinate dehydrogenase; High confidence in function and specificity.
  
 0.944
sdhB2
Succinate dehydrogenase; High confidence in function and specificity.
  
 0.944
sce2757
ABC transporter, substrate binding protein; Family membership.
 
    0.905
sce2646
Oxidoreductase; Specificity unclear.
  
 
 0.901
nuoF
NADH dehydrogenase (ubiquinone); High confidence in function and specificity.
  
 
 0.884
sucD
Succinate--CoA ligase (ADP-forming); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.876
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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