| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fsxA | grpE | sce2888 | sce0004 | Conserved hypothetical membrane protein, FxsA-like; Function unclear. | Chloroplast GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.501 |
| fsxA | htpX | sce2888 | sce8039 | Conserved hypothetical membrane protein, FxsA-like; Function unclear. | Peptidase, M48 family; Family membership; Belongs to the peptidase M48B family. | 0.647 |
| fsxA | kamD | sce2888 | sce2889 | Conserved hypothetical membrane protein, FxsA-like; Function unclear. | Beta-lysine 5,6-aminomutase, alpha subunit; High confidence in function and specificity. | 0.466 |
| fsxA | sce0576 | sce2888 | sce0576 | Conserved hypothetical membrane protein, FxsA-like; Function unclear. | Low molecular weight heat shock protein; Family membership; Belongs to the small heat shock protein (HSP20) family. | 0.515 |
| fsxA | sce0577 | sce2888 | sce0577 | Conserved hypothetical membrane protein, FxsA-like; Function unclear. | Heat shock protein, HSP20 family; Family membership; Belongs to the small heat shock protein (HSP20) family. | 0.515 |
| fsxA | sce2890 | sce2888 | sce2890 | Conserved hypothetical membrane protein, FxsA-like; Function unclear. | Hypothetical protein. | 0.417 |
| fsxA | sce3068 | sce2888 | sce3068 | Conserved hypothetical membrane protein, FxsA-like; Function unclear. | Putative secreted protein. | 0.803 |
| fsxA | sce4954 | sce2888 | sce4954 | Conserved hypothetical membrane protein, FxsA-like; Function unclear. | Heat shock protein, Hsp20 family; Family membership; Belongs to the small heat shock protein (HSP20) family. | 0.515 |
| fsxA | sce7703 | sce2888 | sce7703 | Conserved hypothetical membrane protein, FxsA-like; Function unclear. | Heat shock protein, Hsp20 family; Family membership; Belongs to the small heat shock protein (HSP20) family. | 0.515 |
| grpE | fsxA | sce0004 | sce2888 | Chloroplast GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | Conserved hypothetical membrane protein, FxsA-like; Function unclear. | 0.501 |
| grpE | htpX | sce0004 | sce8039 | Chloroplast GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | Peptidase, M48 family; Family membership; Belongs to the peptidase M48B family. | 0.666 |
| grpE | sce0576 | sce0004 | sce0576 | Chloroplast GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | Low molecular weight heat shock protein; Family membership; Belongs to the small heat shock protein (HSP20) family. | 0.545 |
| grpE | sce0577 | sce0004 | sce0577 | Chloroplast GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | Heat shock protein, HSP20 family; Family membership; Belongs to the small heat shock protein (HSP20) family. | 0.545 |
| grpE | sce4954 | sce0004 | sce4954 | Chloroplast GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | Heat shock protein, Hsp20 family; Family membership; Belongs to the small heat shock protein (HSP20) family. | 0.545 |
| grpE | sce7703 | sce0004 | sce7703 | Chloroplast GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | Heat shock protein, Hsp20 family; Family membership; Belongs to the small heat shock protein (HSP20) family. | 0.545 |
| htpX | fsxA | sce8039 | sce2888 | Peptidase, M48 family; Family membership; Belongs to the peptidase M48B family. | Conserved hypothetical membrane protein, FxsA-like; Function unclear. | 0.647 |
| htpX | grpE | sce8039 | sce0004 | Peptidase, M48 family; Family membership; Belongs to the peptidase M48B family. | Chloroplast GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.666 |
| kamD | fsxA | sce2889 | sce2888 | Beta-lysine 5,6-aminomutase, alpha subunit; High confidence in function and specificity. | Conserved hypothetical membrane protein, FxsA-like; Function unclear. | 0.466 |
| kamD | sce2890 | sce2889 | sce2890 | Beta-lysine 5,6-aminomutase, alpha subunit; High confidence in function and specificity. | Hypothetical protein. | 0.678 |
| sce0576 | fsxA | sce0576 | sce2888 | Low molecular weight heat shock protein; Family membership; Belongs to the small heat shock protein (HSP20) family. | Conserved hypothetical membrane protein, FxsA-like; Function unclear. | 0.515 |