Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fsxAConserved hypothetical membrane protein, FxsA-like; Function unclear. (198 aa)    
Predicted Functional Partners:
sce3068
Putative secreted protein.
  
  
 0.803
htpX
Peptidase, M48 family; Family membership; Belongs to the peptidase M48B family.
   
  
 0.647
sce0576
Low molecular weight heat shock protein; Family membership; Belongs to the small heat shock protein (HSP20) family.
   
    0.515
sce0577
Heat shock protein, HSP20 family; Family membership; Belongs to the small heat shock protein (HSP20) family.
   
    0.515
sce4954
Heat shock protein, Hsp20 family; Family membership; Belongs to the small heat shock protein (HSP20) family.
   
    0.515
sce7703
Heat shock protein, Hsp20 family; Family membership; Belongs to the small heat shock protein (HSP20) family.
   
    0.515
grpE
Chloroplast GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
   
  
 0.501
kamD
Beta-lysine 5,6-aminomutase, alpha subunit; High confidence in function and specificity.
       0.466
sce2890
Hypothetical protein.
       0.417
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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