Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
phoUPhosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake. (248 aa)    
Predicted Functional Partners:
pstB
Phosphate ABC transporter, ATP-binding protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
  
 0.996
pstA
Phosphate ABC transporter, permease protein PstA; High confidence in function and specificity.
  
 0.996
pstC
Phosphate ABC transporter, permease protein PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
  
 0.970
pstS
Phosphate ABC transporter, substrate-binding protein PstS; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
 
  
 0.926
sce8385
Uncharacterized protein conserved in bacteria.
   
    0.808
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
  
    0.723
phoR1
Phosphate sensory box histidine kinase PhoR; High confidence in function and specificity.
 
   
 0.643
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.609
phoB
Phosphate regulon transcriptional regulatory protein phoB; High confidence in function and specificity.
 
  
 0.576
sce1385
Transcriptional regulator, TetR family; Family membership.
   
    0.549
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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