Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sce3010Putative 3-hydroxy-3-methylglutaryl-CoA reductase; Family membership; Belongs to the HMG-CoA reductase family. (424 aa)    
Predicted Functional Partners:
mvk
Mvk protein; Mevalonate kinase.
 0.998
sce6394
Putative Hydroxymethylglutaryl-CoA synthase.
 
 0.997
pcaF
Putative beta-ketoadipyl CoA thiolase; Family membership; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.916
sce7554
Thiolase; Family membership; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.916
sce3181
Probable Hydroxymethylglutaryl-CoA synthase.
 
 
 0.908
idi
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
   
 0.881
sce4206
Diphosphomevalonate decarboxylase; Family membership.
 
  
 0.875
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
   
 
 0.830
sce0049
Thiolase; Family membership; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.823
sce4207
Phosphomevalonate kinase.
 
 
 0.800
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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