STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sce3426Phosphofructokinase-domain containing protein. (399 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; High confidence in function and specificity; Belongs to the pyruvate kinase family.
 
 
 0.834
sce5197
Put. Pyruvate kinase; Family membership; Belongs to the pyruvate kinase family.
  
 
 0.808
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.793
pgi
Glucose-6-phosphate isomerase; High confidence in function and specificity; Belongs to the GPI family.
  
 
 0.782
tpi
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
 0.765
guaA1
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
   
  
 0.729
pgk
Phosphoglycerate kinase; High confidence in function and specificity; Belongs to the phosphoglycerate kinase family.
 
  
 0.694
gap
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); High confidence in function and specificity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
  
 0.685
pfk
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
  
 
0.674
glgP
Phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 
 0.648
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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