Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sce3521Hypothetical protein. (199 aa)    
Predicted Functional Partners:
topB
DNA topoisomerase III; High confidence in function and specificity.
   
 
 0.918
sce0078
ATP-dependent deoxyribonuclease subunit A; Family membership; Belongs to the helicase family. UvrD subfamily.
  
 
 0.850
sce2839
Exodeoxyribonuclease V beta chain; High confidence in function and specificity; Belongs to the helicase family. UvrD subfamily.
  
 
 0.850
dnaN
DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.801
sce3522
Hypothetical protein.
       0.779
polB
DNA-directed DNA polymerase; High confidence in function and specificity.
   
 
 0.750
recQ
ATP-dependent DNA helicase RecQ; High confidence in function and specificity.
   
 
 0.670
sce3523
DNA_LIGASE_A3 domain-containing protein; Unnamed protein product; High confidence in function and specificity.
   
 
 0.636
CAN94224.1
Pseudogene; Family membership.
   
 
 0.610
sce4262
Hypothetical protein.
   
 
 0.581
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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