STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
pyrFPutative Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (260 aa)    
Predicted Functional Partners:
pyrE
Putative orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.992
pyrR
Putative Pyrimidine operon attenuation protein / Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
 
 
 0.990
pyrB
Aspartate carbamoyltransferase; Family membership; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.953
sce2468
Hypothetical protein predicted by Glimmer/Critica.
  
 
 0.938
pyrH
Phosphotransfease with a phosphate group as acceptor; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.929
carA1
Carbamoyl-phosphate synthase; Family membership.
  
  
 0.928
surE1
Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.927
carA2
Carbamoyl-phosphate synthase; Family membership; Belongs to the CarA family.
  
  
 0.922
sce8819
Hypothetical protein; 5-nucleotidase/23-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.
    
 0.912
pyrD
Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
  
 0.908
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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