Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
sce3725ChaC-like family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (194 aa)    
Predicted Functional Partners:
gor
Glutathione-disulfide reductase; Maintains high levels of reduced glutathione.
  
  
 0.918
pepA2
Putative aminopeptidase.
  
  
  0.916
gshB
Glutathione synthetase; High confidence in function and specificity; Belongs to the prokaryotic GSH synthase family.
     
 0.913
oplaH
5-oxoprolinase (ATP-hydrolyzing).
     
 0.904
sce0905
Putative peroxiredoxin 2 family protein/glutaredoxin; Family membership.
     
 0.901
ggt1
Gamma-glutamyltransferase; High confidence in function and specificity.
     
 0.901
ggt2
Gamma-glutamyltransferase; Family membership.
     
 0.901
ggt3
Gamma-glutamyltranferase; Family membership.
     
 0.901
pepN1
Aminopeptidase.
     
  0.900
pepN2
Membrane alanyl aminopeptidase; High confidence in function and specificity.
     
  0.900
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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