Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
surE25'-nucleotidase, cytosolic II; High confidence in function and specificity. (501 aa)    
Predicted Functional Partners:
sucD
Succinate--CoA ligase (ADP-forming); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 
    0.834
topB
DNA topoisomerase III; High confidence in function and specificity.
  
 
 0.810
sce4774
Peptidase M10A; Family membership.
  
     0.633
sce8339
Conserved hypothetical protein with Kelch motif.
  
   0.607
sce6043
Hypothetical protein.
  
 
   0.599
sce6691
Hypothetical protein; Weak evidence for sugar / carbohydrate binding.
  
 
   0.592
sce0518
Probable lipase.
  
   
 0.584
sce6044
Putative transposase; Family membership.
  
 
   0.577
add
Putative Adenosine deaminase; Family membership.
  
  
  0.574
sce5368
Lanthionine synthetase C-like family protein.
  
     0.572
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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