Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sce3748Sugar phosphatase; Specificity unclear. (225 aa)    
Predicted Functional Partners:
sce3746
Sugar kinase; Family membership.
 
 
 0.995
gmhA
Sedoheptulose 7-phosphate isomerase; High confidence in function and specificity.
 
  
 0.993
sce0565
Hypothetical protein; Predicted kinase related to galactokinase and mevalonate kinase.
 
 
 0.988
hisIE
Histidine biosynthesis bifunctional protein HisIE; Family membership; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.928
sce3745
Sugar phosphate nucleotidyltransferase; Family membership.
 
 0.879
hisH
Amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.740
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.711
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
  
 0.696
sce8781
DNA polymerase lambda; High confidence in function and specificity.
    
 0.672
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; High confidence in function and specificity.
  
  
 0.665
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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