| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaE2 | dnaG | sce3750 | sce4446 | DNA polymerase III, alpha subunit; High confidence in function and specificity. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.751 |
| dnaE2 | dnaN | sce3750 | sce8164 | DNA polymerase III, alpha subunit; High confidence in function and specificity. | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.995 |
| dnaE2 | dnaX | sce3750 | sce0259 | DNA polymerase III, alpha subunit; High confidence in function and specificity. | DNA polymerase III subunit Tau; High confidence in function and specificity. | 0.988 |
| dnaE2 | holA | sce3750 | sce5298 | DNA polymerase III, alpha subunit; High confidence in function and specificity. | Putative DNA polymerase III, delta subunit; Family membership. | 0.991 |
| dnaE2 | holB | sce3750 | sce1791 | DNA polymerase III, alpha subunit; High confidence in function and specificity. | DNA polymerase III delta' subunit. | 0.985 |
| dnaE2 | sce1712 | sce3750 | sce1712 | DNA polymerase III, alpha subunit; High confidence in function and specificity. | Exonuclease. | 0.984 |
| dnaE2 | sce2627 | sce3750 | sce2627 | DNA polymerase III, alpha subunit; High confidence in function and specificity. | Single-strand binding protein; High confidence in function and specificity. | 0.793 |
| dnaE2 | sce7572 | sce3750 | sce7572 | DNA polymerase III, alpha subunit; High confidence in function and specificity. | DNA polymerase III, epsilon subunit; Specificity unclear. | 0.984 |
| dnaE2 | sce8612 | sce3750 | sce8612 | DNA polymerase III, alpha subunit; High confidence in function and specificity. | Single-stranded DNA binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.837 |
| dnaE2 | ssb | sce3750 | sce2625 | DNA polymerase III, alpha subunit; High confidence in function and specificity. | ssDNA-binding protein; High confidence in function and specificity. | 0.840 |
| dnaG | dnaE2 | sce4446 | sce3750 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA polymerase III, alpha subunit; High confidence in function and specificity. | 0.751 |
| dnaG | dnaN | sce4446 | sce8164 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.678 |
| dnaG | dnaX | sce4446 | sce0259 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA polymerase III subunit Tau; High confidence in function and specificity. | 0.546 |
| dnaG | holB | sce4446 | sce1791 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA polymerase III delta' subunit. | 0.483 |
| dnaG | sce8612 | sce4446 | sce8612 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Single-stranded DNA binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.417 |
| dnaN | dnaE2 | sce8164 | sce3750 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III, alpha subunit; High confidence in function and specificity. | 0.995 |
| dnaN | dnaG | sce8164 | sce4446 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.678 |
| dnaN | dnaX | sce8164 | sce0259 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III subunit Tau; High confidence in function and specificity. | 0.993 |
| dnaN | holA | sce8164 | sce5298 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative DNA polymerase III, delta subunit; Family membership. | 0.996 |
| dnaN | holB | sce8164 | sce1791 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III delta' subunit. | 0.993 |