node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
galE3 | gmk | sce3760 | sce3762 | UDP-glucose 4-epimerase; High confidence in function and specificity. | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.715 |
galE3 | mtaP | sce3760 | sce3763 | UDP-glucose 4-epimerase; High confidence in function and specificity. | 5'-methyl-5-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.711 |
galE3 | sce3764 | sce3760 | sce3764 | UDP-glucose 4-epimerase; High confidence in function and specificity. | Carbohydrate kinase, PfkB family; Specificity unclear. | 0.500 |
galE3 | yloC | sce3760 | sce3761 | UDP-glucose 4-epimerase; High confidence in function and specificity. | Uncharacterized stress-induced protein. | 0.718 |
gmk | galE3 | sce3762 | sce3760 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | UDP-glucose 4-epimerase; High confidence in function and specificity. | 0.715 |
gmk | mtaP | sce3762 | sce3763 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 5'-methyl-5-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.781 |
gmk | sce3764 | sce3762 | sce3764 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Carbohydrate kinase, PfkB family; Specificity unclear. | 0.544 |
gmk | yloC | sce3762 | sce3761 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Uncharacterized stress-induced protein. | 0.953 |
hisA | sce3764 | sce2813 | sce3764 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; High confidence in function and specificity. | Carbohydrate kinase, PfkB family; Specificity unclear. | 0.622 |
mtaP | galE3 | sce3763 | sce3760 | 5'-methyl-5-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | UDP-glucose 4-epimerase; High confidence in function and specificity. | 0.711 |
mtaP | gmk | sce3763 | sce3762 | 5'-methyl-5-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.781 |
mtaP | sce3764 | sce3763 | sce3764 | 5'-methyl-5-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Carbohydrate kinase, PfkB family; Specificity unclear. | 0.597 |
mtaP | yloC | sce3763 | sce3761 | 5'-methyl-5-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Uncharacterized stress-induced protein. | 0.772 |
ribH | sce3764 | sce7268 | sce3764 | Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | Carbohydrate kinase, PfkB family; Specificity unclear. | 0.474 |
sce0871 | sce3764 | sce0871 | sce3764 | Hypothetical protein. | Carbohydrate kinase, PfkB family; Specificity unclear. | 0.488 |
sce1297 | sce3764 | sce1297 | sce3764 | Hypothetical protein predicted by Glimmer/Critica. | Carbohydrate kinase, PfkB family; Specificity unclear. | 0.488 |
sce2382 | sce3764 | sce2382 | sce3764 | Putative secreted protein. | Carbohydrate kinase, PfkB family; Specificity unclear. | 0.613 |
sce3764 | galE3 | sce3764 | sce3760 | Carbohydrate kinase, PfkB family; Specificity unclear. | UDP-glucose 4-epimerase; High confidence in function and specificity. | 0.500 |
sce3764 | gmk | sce3764 | sce3762 | Carbohydrate kinase, PfkB family; Specificity unclear. | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.544 |
sce3764 | hisA | sce3764 | sce2813 | Carbohydrate kinase, PfkB family; Specificity unclear. | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; High confidence in function and specificity. | 0.622 |