| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| apt | gmk | sce2983 | sce3762 | Putative Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.679 |
| apt | mtaP | sce2983 | sce3763 | Putative Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'-methyl-5-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.955 |
| apt | purA | sce2983 | sce8895 | Putative Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.825 |
| apt | sce3764 | sce2983 | sce3764 | Putative Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Carbohydrate kinase, PfkB family; Specificity unclear. | 0.427 |
| galE3 | gmk | sce3760 | sce3762 | UDP-glucose 4-epimerase; High confidence in function and specificity. | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.709 |
| galE3 | mtaP | sce3760 | sce3763 | UDP-glucose 4-epimerase; High confidence in function and specificity. | 5'-methyl-5-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.708 |
| galE3 | sce3764 | sce3760 | sce3764 | UDP-glucose 4-epimerase; High confidence in function and specificity. | Carbohydrate kinase, PfkB family; Specificity unclear. | 0.498 |
| galE3 | yloC | sce3760 | sce3761 | UDP-glucose 4-epimerase; High confidence in function and specificity. | Uncharacterized stress-induced protein. | 0.718 |
| gmk | apt | sce3762 | sce2983 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.679 |
| gmk | galE3 | sce3762 | sce3760 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | UDP-glucose 4-epimerase; High confidence in function and specificity. | 0.709 |
| gmk | mtaP | sce3762 | sce3763 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 5'-methyl-5-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.777 |
| gmk | purA | sce3762 | sce8895 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.464 |
| gmk | sce3764 | sce3762 | sce3764 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Carbohydrate kinase, PfkB family; Specificity unclear. | 0.511 |
| gmk | yloC | sce3762 | sce3761 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Uncharacterized stress-induced protein. | 0.949 |
| hisA | sce3764 | sce2813 | sce3764 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; High confidence in function and specificity. | Carbohydrate kinase, PfkB family; Specificity unclear. | 0.649 |
| holA | sce3764 | sce5298 | sce3764 | Putative DNA polymerase III, delta subunit; Family membership. | Carbohydrate kinase, PfkB family; Specificity unclear. | 0.409 |
| mtaP | apt | sce3763 | sce2983 | 5'-methyl-5-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Putative Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.955 |
| mtaP | galE3 | sce3763 | sce3760 | 5'-methyl-5-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | UDP-glucose 4-epimerase; High confidence in function and specificity. | 0.708 |
| mtaP | gmk | sce3763 | sce3762 | 5'-methyl-5-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.777 |
| mtaP | sce3764 | sce3763 | sce3764 | 5'-methyl-5-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | Carbohydrate kinase, PfkB family; Specificity unclear. | 0.578 |
