Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
aceF1Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (438 aa)    
Predicted Functional Partners:
pdhB1
Pyruvate dehydrogenase (acetyl-transferring); High confidence in function and specificity.
 0.999
pdhB2
Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
aceE
Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.998
pdhD
Pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase); High confidence in function and specificity.
 0.998
pdhA
Pyruvate dehydrogenase (acetyl-transferring); High confidence in function and specificity.
 
 0.995
sce8001
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring).
 0.995
sucA
Oxoglutarate dehydrogenase (succinyl-transferring); High confidence in function and specificity.
 0.989
sce1736
Citrate synthase (EC 2.3.3.1).
  
 0.972
cis1
Citrate synthase; Family membership; Belongs to the citrate synthase family.
  
 0.968
cis2
Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family.
  
 0.968
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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