| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carA1 | pyrB | sce2399 | sce3822 | Carbamoyl-phosphate synthase; Family membership. | Aspartate carbamoyltransferase; Family membership; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carA1 | pyrC | sce2399 | sce4269 | Carbamoyl-phosphate synthase; Family membership. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.988 |
| carA1 | pyrF | sce2399 | sce3701 | Carbamoyl-phosphate synthase; Family membership. | Putative Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.928 |
| carA1 | pyrR | sce2399 | sce3821 | Carbamoyl-phosphate synthase; Family membership. | Putative Pyrimidine operon attenuation protein / Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.914 |
| carA1 | sce2468 | sce2399 | sce2468 | Carbamoyl-phosphate synthase; Family membership. | Hypothetical protein predicted by Glimmer/Critica. | 0.610 |
| carA1 | yeiA | sce2399 | sce6397 | Carbamoyl-phosphate synthase; Family membership. | Dihydropyrimidine dehydrogenase; Family membership. | 0.907 |
| pdp | ppnP | sce2436 | sce4830 | Pyrimidine-nucleoside phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Protein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.917 |
| pdp | pyrR | sce2436 | sce3821 | Pyrimidine-nucleoside phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Putative Pyrimidine operon attenuation protein / Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.919 |
| pdp | sce2468 | sce2436 | sce2468 | Pyrimidine-nucleoside phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Hypothetical protein predicted by Glimmer/Critica. | 0.934 |
| pdp | surE1 | sce2436 | sce2984 | Pyrimidine-nucleoside phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.919 |
| pdp | yeiA | sce2436 | sce6397 | Pyrimidine-nucleoside phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Dihydropyrimidine dehydrogenase; Family membership. | 0.918 |
| ppnP | pdp | sce4830 | sce2436 | Protein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | Pyrimidine-nucleoside phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.917 |
| ppnP | pyrR | sce4830 | sce3821 | Protein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | Putative Pyrimidine operon attenuation protein / Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.917 |
| ppnP | sce2468 | sce4830 | sce2468 | Protein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | Hypothetical protein predicted by Glimmer/Critica. | 0.900 |
| ppnP | surE1 | sce4830 | sce2984 | Protein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
| ppnP | yeiA | sce4830 | sce6397 | Protein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | Dihydropyrimidine dehydrogenase; Family membership. | 0.900 |
| pyrB | carA1 | sce3822 | sce2399 | Aspartate carbamoyltransferase; Family membership; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Carbamoyl-phosphate synthase; Family membership. | 0.999 |
| pyrB | pyrC | sce3822 | sce4269 | Aspartate carbamoyltransferase; Family membership; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
| pyrB | pyrF | sce3822 | sce3701 | Aspartate carbamoyltransferase; Family membership; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Putative Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.953 |
| pyrB | pyrR | sce3822 | sce3821 | Aspartate carbamoyltransferase; Family membership; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Putative Pyrimidine operon attenuation protein / Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.998 |