| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gmk | mazG | sce3762 | sce4803 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Hypothetical protein; Family membership. | 0.902 |
| gmk | ndk | sce3762 | sce2949 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.927 |
| gmk | nrdA1 | sce3762 | sce0379 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.908 |
| gmk | nrdA2 | sce3762 | sce3875 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.908 |
| gmk | nrdB | sce3762 | sce3876 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleotide-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.913 |
| gmk | rel | sce3762 | sce3845 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.929 |
| gmk | sce6063 | sce3762 | sce6063 | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Hypothetical protein predicted by Glimmer/Critica; Specificity unclear. | 0.926 |
| mazG | gmk | sce4803 | sce3762 | Hypothetical protein; Family membership. | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.902 |
| mazG | ndk | sce4803 | sce2949 | Hypothetical protein; Family membership. | Putative Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
| mazG | rel | sce4803 | sce3845 | Hypothetical protein; Family membership. | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.935 |
| mazG | sce3998 | sce4803 | sce3998 | Hypothetical protein; Family membership. | Unnamed protein product; Family membership. | 0.901 |
| mazG | sce6063 | sce4803 | sce6063 | Hypothetical protein; Family membership. | Hypothetical protein predicted by Glimmer/Critica; Specificity unclear. | 0.494 |
| ndk | gmk | sce2949 | sce3762 | Putative Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Putative Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.927 |
| ndk | mazG | sce2949 | sce4803 | Putative Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Hypothetical protein; Family membership. | 0.900 |
| ndk | nrdA1 | sce2949 | sce0379 | Putative Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Putative Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.917 |
| ndk | nrdA2 | sce2949 | sce3875 | Putative Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.917 |
| ndk | nrdB | sce2949 | sce3876 | Putative Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribonucleotide-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.919 |
| ndk | rel | sce2949 | sce3845 | Putative Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.918 |
| ndk | sce3998 | sce2949 | sce3998 | Putative Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Unnamed protein product; Family membership. | 0.911 |
| ndk | sce6063 | sce2949 | sce6063 | Putative Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Hypothetical protein predicted by Glimmer/Critica; Specificity unclear. | 0.918 |
