| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroC | dhbC | sce4843 | sce5042 | 5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | DhbC protein; High confidence in function and specificity. | 0.932 |
| aroC | mxcD | sce4843 | sce3879 | 5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | MxcD protein; High confidence in function and specificity. | 0.903 |
| aroC | pheA1 | sce4843 | sce1746 | 5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | PheA1 protein; Family membership. | 0.980 |
| dhbC | aroC | sce5042 | sce4843 | DhbC protein; High confidence in function and specificity. | 5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.932 |
| dhbC | menD | sce5042 | sce3012 | DhbC protein; High confidence in function and specificity. | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). | 0.989 |
| dhbC | mxcD | sce5042 | sce3879 | DhbC protein; High confidence in function and specificity. | MxcD protein; High confidence in function and specificity. | 0.918 |
| dhbC | mxcE | sce5042 | sce3880 | DhbC protein; High confidence in function and specificity. | (2,3-dihydroxybenzoyl)adenylate synthase; High confidence in function and specificity. | 0.948 |
| dhbC | mxcF | sce5042 | sce3881 | DhbC protein; High confidence in function and specificity. | Isochorismatase; High confidence in function and specificity. | 0.997 |
| dhbC | pheA1 | sce5042 | sce1746 | DhbC protein; High confidence in function and specificity. | PheA1 protein; Family membership. | 0.893 |
| dhbC | sce0345 | sce5042 | sce0345 | DhbC protein; High confidence in function and specificity. | NRPS/PKS hybrid; Family membership. | 0.923 |
| dhbC | sce2387 | sce5042 | sce2387 | DhbC protein; High confidence in function and specificity. | Non-ribosomal peptide synthetase; Family membership. | 0.937 |
| dhbC | sce6823 | sce5042 | sce6823 | DhbC protein; High confidence in function and specificity. | NRPS/PKS hybrid. | 0.966 |
| dhbC | sce8255 | sce5042 | sce8255 | DhbC protein; High confidence in function and specificity. | Non-ribosomal peptide synthetase; Family membership. | 0.907 |
| menD | dhbC | sce3012 | sce5042 | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). | DhbC protein; High confidence in function and specificity. | 0.989 |
| menD | mxcD | sce3012 | sce3879 | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). | MxcD protein; High confidence in function and specificity. | 0.978 |
| mxcD | aroC | sce3879 | sce4843 | MxcD protein; High confidence in function and specificity. | 5-enolpyruvylshikimate-3-phosphate phospholyase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.903 |
| mxcD | dhbC | sce3879 | sce5042 | MxcD protein; High confidence in function and specificity. | DhbC protein; High confidence in function and specificity. | 0.918 |
| mxcD | menD | sce3879 | sce3012 | MxcD protein; High confidence in function and specificity. | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). | 0.978 |
| mxcD | mxcE | sce3879 | sce3880 | MxcD protein; High confidence in function and specificity. | (2,3-dihydroxybenzoyl)adenylate synthase; High confidence in function and specificity. | 0.994 |
| mxcD | mxcF | sce3879 | sce3881 | MxcD protein; High confidence in function and specificity. | Isochorismatase; High confidence in function and specificity. | 0.999 |