STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mxcLGlutamate-1-semialdehyde 2,1-aminomutase; High confidence in function and specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (440 aa)    
Predicted Functional Partners:
uroS
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.953
sce8261
Polyketide synthase type I; Family membership.
    
 0.926
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.914
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.906
sce8219
AMP-dependent synthetase and ligase; Belongs to the ATP-dependent AMP-binding enzyme family.
 
    0.900
mxcG
Nonribosomal peptide synthetase; High confidence in function and specificity.
   
 0.894
sce0436
AMP-dependent synthetase and ligase.
 
    0.875
sce8262
Non-ribosomal peptide synthetase; Family membership.
 
  
 0.853
hemD
Uroporphyrinogen-III synthase; Family membership.
 
  
 0.770
sce8255
Non-ribosomal peptide synthetase; Family membership.
    
 0.769
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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