| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaN | sce0906 | sce8164 | sce0906 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | methylated-DNA--protein-cysteine methyltransferase; Family membership. | 0.781 |
| dnaN | sce1381 | sce8164 | sce1381 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative nuclease; Family membership. | 0.887 |
| dnaN | sce3935 | sce8164 | sce3935 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.831 |
| dnaN | xthA | sce8164 | sce8116 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III; High confidence in function and specificity. | 0.887 |
| hemN | sce3935 | sce3846 | sce3935 | Coproporphyrinogen oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.561 |
| msrA2 | sce3935 | sce7999 | sce3935 | Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.471 |
| sce0295 | sce3935 | sce0295 | sce3935 | Putative NUDIX hydrolase; Family membership. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.432 |
| sce0906 | dnaN | sce0906 | sce8164 | methylated-DNA--protein-cysteine methyltransferase; Family membership. | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.781 |
| sce0906 | sce1381 | sce0906 | sce1381 | methylated-DNA--protein-cysteine methyltransferase; Family membership. | Putative nuclease; Family membership. | 0.634 |
| sce0906 | sce3935 | sce0906 | sce3935 | methylated-DNA--protein-cysteine methyltransferase; Family membership. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.501 |
| sce0906 | xthA | sce0906 | sce8116 | methylated-DNA--protein-cysteine methyltransferase; Family membership. | Exodeoxyribonuclease III; High confidence in function and specificity. | 0.634 |
| sce1381 | dnaN | sce1381 | sce8164 | Putative nuclease; Family membership. | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.887 |
| sce1381 | sce0906 | sce1381 | sce0906 | Putative nuclease; Family membership. | methylated-DNA--protein-cysteine methyltransferase; Family membership. | 0.634 |
| sce1381 | sce3935 | sce1381 | sce3935 | Putative nuclease; Family membership. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.861 |
| sce1381 | xthA | sce1381 | sce8116 | Putative nuclease; Family membership. | Exodeoxyribonuclease III; High confidence in function and specificity. | 0.900 |
| sce3935 | dnaN | sce3935 | sce8164 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.831 |
| sce3935 | hemN | sce3935 | sce3846 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Coproporphyrinogen oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.561 |
| sce3935 | msrA2 | sce3935 | sce7999 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.471 |
| sce3935 | sce0295 | sce3935 | sce0295 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Putative NUDIX hydrolase; Family membership. | 0.432 |
| sce3935 | sce0906 | sce3935 | sce0906 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | methylated-DNA--protein-cysteine methyltransferase; Family membership. | 0.501 |
