Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sce4004Transcriptional regulator, DeoR family; Specificity unclear. (266 aa)    
Predicted Functional Partners:
sce4081
Acyl-activating enzyme; Family membership.
    
   0.763
glpA
Glycerol-3-phosphate dehydrogenase; Family membership; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.703
sce4003
Permease of the major facilitator superfamily; Specificity unclear.
 
   
 0.688
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
 
  
 0.660
fruB
Fructose-specific MTP; High confidence in function and specificity; Belongs to the PEP-utilizing enzyme family.
 
  
 0.624
glpD
GlpD protein; Family membership.
 
  
 0.609
sce2727
Two-component system sensor protein; Specificity unclear.
  
  
 0.547
sce5768
Nitrogen regulatory IIA protein homolog; Family membership.
 
  
 0.540
ptsN
Nitrogen regulatory IIA protein.
 
  
 0.522
sce5375
Unnamed protein product; Family membership; Belongs to the FGGY kinase family.
 
   
 0.517
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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