node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
crtD | sce4024 | sce0585 | sce4024 | Putative methoxyneurosporene dehydrogenase; Family membership. | Putative cobalamin binding protein. | 0.430 |
deoC | sce4024 | sce5008 | sce4024 | Putative Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. | Putative cobalamin binding protein. | 0.769 |
hemE | metH1 | sce8628 | sce5871 | Putative Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.454 |
hemE | metH2 | sce8628 | sce7733 | Putative Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.454 |
hemE | sce4024 | sce8628 | sce4024 | Putative Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Putative cobalamin binding protein. | 0.404 |
hemE | sce8634 | sce8628 | sce8634 | Putative Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Methylenetetrahydrofolate reductase family protein; Family membership. | 0.445 |
metH1 | hemE | sce5871 | sce8628 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Putative Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.454 |
metH1 | metH2 | sce5871 | sce7733 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.983 |
metH1 | sce4024 | sce5871 | sce4024 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Putative cobalamin binding protein. | 0.412 |
metH1 | sce8634 | sce5871 | sce8634 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methylenetetrahydrofolate reductase family protein; Family membership. | 0.995 |
metH2 | hemE | sce7733 | sce8628 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Putative Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.454 |
metH2 | metH1 | sce7733 | sce5871 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.983 |
metH2 | sce4024 | sce7733 | sce4024 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Putative cobalamin binding protein. | 0.412 |
metH2 | sce8634 | sce7733 | sce8634 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methylenetetrahydrofolate reductase family protein; Family membership. | 0.995 |
sce4022 | sce4023 | sce4022 | sce4023 | Anti-anti sigma factor protein; Specificity unclear. | Putative uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. | 0.651 |
sce4022 | sce4024 | sce4022 | sce4024 | Anti-anti sigma factor protein; Specificity unclear. | Putative cobalamin binding protein. | 0.414 |
sce4023 | sce4022 | sce4023 | sce4022 | Putative uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. | Anti-anti sigma factor protein; Specificity unclear. | 0.651 |
sce4023 | sce4024 | sce4023 | sce4024 | Putative uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. | Putative cobalamin binding protein. | 0.480 |
sce4024 | crtD | sce4024 | sce0585 | Putative cobalamin binding protein. | Putative methoxyneurosporene dehydrogenase; Family membership. | 0.430 |
sce4024 | deoC | sce4024 | sce5008 | Putative cobalamin binding protein. | Putative Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. | 0.769 |