Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sce4090Adenylate cyclase family 3 (some proteins contain HAMP domain). (458 aa)    
Predicted Functional Partners:
sce1725
Putative adenylate cyclase.
  
     0.739
sce1501
Putative adenylate/guanylate cyclase.
  
     0.732
cyaX
Putative adenylate cyclase; Family membership; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
     0.684
sce0859
Hypothetical protein; Metal-dependent hydrolases of the beta-lactamase superfamily I.
 
     0.675
sce9034
Hypothetical protein; Metal-dependent hydrolases of the beta-lactamase superfamily I.
 
     0.675
sce7616
Adenylate cyclase; Family membership.
 
     0.672
sce3998
Unnamed protein product; Family membership.
  
 
   0.603
sce4318
cAMP-binding protein Probable transcriptional regulatory protein; Specificity unclear.
  
   0.514
sce8187
cAMP-dependent protein kinase regulatory subunit; Family membership.
  
   0.511
sce2730
Protein kinase; Family membership.
  
     0.484
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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