Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sce4152Transcriptional regulator lacI family; Specificity unclear. (341 aa)    
Predicted Functional Partners:
fruB
Fructose-specific MTP; High confidence in function and specificity; Belongs to the PEP-utilizing enzyme family.
   
 
 0.800
gltB1
Glutamate synthase (NADPH); High confidence in function and specificity.
    
 
 0.794
serA1
Phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.580
bglA4
Beta-glucosidase; High confidence in function and specificity.
 
     0.522
ptsH
Phosphocarrier protein HPr; High confidence in function and specificity.
 
 
 
 0.484
sce4004
Transcriptional regulator, DeoR family; Specificity unclear.
  
   
 0.480
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.478
sce3064
Alpha amylase, catalytic region; Family membership.
 
  
 0.453
sce7780
Alpha-amylase family protein; Family membership.
 
  
 0.452
sce5375
Unnamed protein product; Family membership; Belongs to the FGGY kinase family.
 
 
 
 0.438
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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