Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ppsA1Phosphoenolpyruvate synthase; High confidence in function and specificity. (870 aa)    
Predicted Functional Partners:
sce5851
Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
 
  
 0.572
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.569
pyk
Pyruvate kinase; High confidence in function and specificity; Belongs to the pyruvate kinase family.
     
 0.558
sce5197
Put. Pyruvate kinase; Family membership; Belongs to the pyruvate kinase family.
     
 0.558
maeB1
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); High confidence in function and specificity.
   
 
 0.537
maeB2
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); Family membership.
   
 
 0.537
sce4176
Protein kinase; Family membership.
       0.488
sce7474
Hypothetical protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
  
     0.429
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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