STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvkMvk protein; Mevalonate kinase. (342 aa)    
Predicted Functional Partners:
sce3010
Putative 3-hydroxy-3-methylglutaryl-CoA reductase; Family membership; Belongs to the HMG-CoA reductase family.
 0.998
sce4207
Phosphomevalonate kinase.
 
  
  0.995
sce4206
Diphosphomevalonate decarboxylase; Family membership.
 
  
 0.993
sce4204
Geranyltranstransferase; Family membership; Belongs to the FPP/GGPP synthase family.
 
  
 0.872
sce6394
Putative Hydroxymethylglutaryl-CoA synthase.
 
  
 0.854
idi
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
   
 0.824
sce3181
Probable Hydroxymethylglutaryl-CoA synthase.
 
  
 0.744
ispB
Trans-octaprenyltranstransferase; Family membership; Belongs to the FPP/GGPP synthase family.
 
  
 0.485
sce4203
Hypothetical protein.
       0.479
guaA1
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
 
  
 0.476
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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