node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bioA | bioB | sce0693 | sce4247 | Adenosylmethionine--8-amino-7-oxononanoate transaminase; Family membership; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.997 |
bioA | bioD | sce0693 | sce8161 | Adenosylmethionine--8-amino-7-oxononanoate transaminase; Family membership; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Hypothetical protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.997 |
bioA | bioF1 | sce0693 | sce2880 | Adenosylmethionine--8-amino-7-oxononanoate transaminase; Family membership; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; Family membership. | 0.976 |
bioA | bioF2 | sce0693 | sce8160 | Adenosylmethionine--8-amino-7-oxononanoate transaminase; Family membership; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Putative 8-amino-7-oxononanoate synthase; Family membership. | 0.991 |
bioA | dapB | sce0693 | sce8028 | Adenosylmethionine--8-amino-7-oxononanoate transaminase; Family membership; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.580 |
bioA | kbl | sce0693 | sce7278 | Adenosylmethionine--8-amino-7-oxononanoate transaminase; Family membership; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.805 |
bioA | sce4915 | sce0693 | sce4915 | Adenosylmethionine--8-amino-7-oxononanoate transaminase; Family membership; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Urea amidolyase-related protein. | 0.518 |
bioB | bioA | sce4247 | sce0693 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Adenosylmethionine--8-amino-7-oxononanoate transaminase; Family membership; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.997 |
bioB | bioD | sce4247 | sce8161 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Hypothetical protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.997 |
bioB | bioF1 | sce4247 | sce2880 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 8-amino-7-oxononanoate synthase; Family membership. | 0.853 |
bioB | bioF2 | sce4247 | sce8160 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Putative 8-amino-7-oxononanoate synthase; Family membership. | 0.914 |
bioB | birA | sce4247 | sce2576 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Biotin-(acetyl-CoA-carboxylase) ligase; Family membership. | 0.936 |
bioB | dapB | sce4247 | sce8028 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.508 |
bioB | kbl | sce4247 | sce7278 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.833 |
bioB | nadA | sce4247 | sce7425 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.585 |
bioB | sce4915 | sce4247 | sce4915 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Urea amidolyase-related protein. | 0.616 |
bioB | thiC | sce4247 | sce4250 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Thiamin biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.712 |
bioD | bioA | sce8161 | sce0693 | Hypothetical protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Adenosylmethionine--8-amino-7-oxononanoate transaminase; Family membership; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.997 |
bioD | bioB | sce8161 | sce4247 | Hypothetical protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.997 |
bioD | bioF1 | sce8161 | sce2880 | Hypothetical protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 8-amino-7-oxononanoate synthase; Family membership. | 0.908 |