STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zwf1Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (529 aa)    
Predicted Functional Partners:
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 
 0.998
gnd1
Phosphogluconate dehydrogenase; High confidence in function and specificity.
  
 0.982
gnd2
Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
 
 0.970
pgi
Glucose-6-phosphate isomerase; High confidence in function and specificity; Belongs to the GPI family.
  
 
 0.967
glk
Glk protein; High confidence in function and specificity; Belongs to the bacterial glucokinase family.
 
 
 0.934
gap
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); High confidence in function and specificity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.921
sce6056
Hypothetical protein.
    
 0.916
zwf2
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
  
 
0.910
pgm3
Pgm3 protein; High confidence in function and specificity.
  
 0.886
pyk
Pyruvate kinase; High confidence in function and specificity; Belongs to the pyruvate kinase family.
  
 
 0.856
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
Server load: very high (>100%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.