STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rocA1-pyrroline-5-carboxylate dehydrogenase; High confidence in function and specificity. (546 aa)    
Predicted Functional Partners:
gdhA1
Glutamate dehydrogenase; Family membership; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.917
gdhA2
Glutamate dehydrogenase; Family membership; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.917
gdhA3
Glutamate dehydrogenase (NADP(+)); High confidence in function and specificity; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.917
aspB1
Aspartate transaminase; Family membership.
   
 0.908
glnA1
GlnA1 protein; Family membership; Belongs to the glutamine synthetase family.
  
 
 0.907
glnA2
Glutamate--ammonia ligase; High confidence in function and specificity.
  
 
 0.907
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 
 0.906
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
     
 0.905
gltD
Glutamate synthase (NADPH); High confidence in function and specificity.
    
 0.905
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
     
 0.904
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.