Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilT2Twitching motility protein. (379 aa)    
Predicted Functional Partners:
pilB
Type IV pilus biogenesis protein PilB.
 
  
0.850
pilD
Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
   
 0.817
pulF
PulF protein; Type II secretory pathway component PulF.
 
  
 0.806
gspF
General secretion pathway protein F.
 
  
 0.805
pilM
Tfp pilus assembly protein, ATPase PilM.
 
   
 0.798
sce2471
Hypothetical protein predicted by Glimmer/Critica.
 
  
 0.770
pilQ
Type 4 fimbrial biogenesis protein PilQ; Specificity unclear.
 
   
 0.566
sce4466
FHA domain-containing protein; Unnamed protein product; Hypothetical protein.
       0.543
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
       0.448
pilO
PilO protein; High confidence in function and specificity.
 
  
 0.408
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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