STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypCHydrogenase expression/formation protein; High confidence in function and specificity. (81 aa)    
Predicted Functional Partners:
hypD
Hydrogenase expression/formation protein hypD2; Belongs to the HypD family.
 
 
 0.999
hypE
Hydrogenase expression/formation protein HypE.
 
 
 0.997
hypF
Hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
 
 0.974
hypA
Hydrogenase nickel insertion protein HypA,putative; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.948
hoxH
Hypothetical protein; Coenzyme F420-reducing hydrogenase alpha subunit.
 
   
 0.905
ureG
Urease accessory protein G; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
  
 0.881
hupD
Hydrogenase expression/formation protein hupD.
  
  
 0.859
sce4574
Putative hydrogenase; Family membership.
 
   
 0.845
sce4573
Hydroxylase or oxidoreductase; Family membership.
       0.787
sce4572
Putative cyclic nucleotide-binding protein.
 
     0.758
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.