| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| iscU | sce4643 | sce7330 | sce4643 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Probable cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.942 |
| iscU | sce8911 | sce7330 | sce8911 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Probable class-V aminotransferase. | 0.942 |
| iscU | trxB | sce7330 | sce7636 | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Thioredoxin-disulfide reductase; High confidence in function and specificity. | 0.416 |
| metB1 | metB2 | sce6169 | sce7598 | Cystathionine gamma-synthase; Family membership. | Cystathionine gamma-synthase. | 0.913 |
| metB1 | sce4643 | sce6169 | sce4643 | Cystathionine gamma-synthase; Family membership. | Probable cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.901 |
| metB1 | sce8911 | sce6169 | sce8911 | Cystathionine gamma-synthase; Family membership. | Probable class-V aminotransferase. | 0.901 |
| metB2 | metB1 | sce7598 | sce6169 | Cystathionine gamma-synthase. | Cystathionine gamma-synthase; Family membership. | 0.913 |
| metB2 | sce4643 | sce7598 | sce4643 | Cystathionine gamma-synthase. | Probable cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.901 |
| metB2 | sce8911 | sce7598 | sce8911 | Cystathionine gamma-synthase. | Probable class-V aminotransferase. | 0.901 |
| sce1441 | sce1442 | sce1441 | sce1442 | Putative nucleotide-binding protein; Family membership. | Putative nucleotide-binding protein. | 0.550 |
| sce1441 | sce4643 | sce1441 | sce4643 | Putative nucleotide-binding protein; Family membership. | Probable cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.569 |
| sce1442 | sce1441 | sce1442 | sce1441 | Putative nucleotide-binding protein. | Putative nucleotide-binding protein; Family membership. | 0.550 |
| sce1442 | sce4643 | sce1442 | sce4643 | Putative nucleotide-binding protein. | Probable cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.549 |
| sce4642 | sce4643 | sce4642 | sce4643 | Putative nucleotide-binding protein; High confidence in function and specificity. | Probable cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.957 |
| sce4642 | sce4644 | sce4642 | sce4644 | Putative nucleotide-binding protein; High confidence in function and specificity. | Rhodanese-like domain-containing protein; Family membership. | 0.451 |
| sce4643 | iscU | sce4643 | sce7330 | Probable cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.942 |
| sce4643 | metB1 | sce4643 | sce6169 | Probable cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | Cystathionine gamma-synthase; Family membership. | 0.901 |
| sce4643 | metB2 | sce4643 | sce7598 | Probable cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | Cystathionine gamma-synthase. | 0.901 |
| sce4643 | sce1441 | sce4643 | sce1441 | Probable cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | Putative nucleotide-binding protein; Family membership. | 0.569 |
| sce4643 | sce1442 | sce4643 | sce1442 | Probable cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | Putative nucleotide-binding protein. | 0.549 |