| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hycD | hycE | sce4800 | sce4797 | Formate hydrogenlyase subunit; High confidence in function and specificity. | NAD-dependent dehydrogenase subunit. | 0.998 |
| hycD | hycG | sce4800 | sce4796 | Formate hydrogenlyase subunit; High confidence in function and specificity. | NAD-dependent dehydrogenase subunit. | 0.999 |
| hycD | hyfB | sce4800 | sce4801 | Formate hydrogenlyase subunit; High confidence in function and specificity. | Hydrogenase-4 component B; High confidence in function and specificity. | 0.993 |
| hycD | hyfF | sce4800 | sce4798 | Formate hydrogenlyase subunit; High confidence in function and specificity. | Hydrogenase-4 component F; High confidence in function and specificity. | 0.993 |
| hycD | mnhD | sce4800 | sce1933 | Formate hydrogenlyase subunit; High confidence in function and specificity. | Putative Na(+)/H(+) antiporter subunit D; Family membership. | 0.877 |
| hycD | nuoC2 | sce4800 | sce9060 | Formate hydrogenlyase subunit; High confidence in function and specificity. | NADH dehydrogenase (ubiquinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.; Belongs to the complex I 30 kDa subunit family. | 0.574 |
| hycD | nuoD2 | sce4800 | sce9061 | Formate hydrogenlyase subunit; High confidence in function and specificity. | NADH dehydrogenase (ubiquinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.; Belongs to the complex I 49 kDa subunit family. | 0.691 |
| hycD | phaA | sce4800 | sce8577 | Formate hydrogenlyase subunit; High confidence in function and specificity. | pH adaptation potassium efflux protein PhaA; High confidence in function and specificity. | 0.615 |
| hycD | phaD | sce4800 | sce8579 | Formate hydrogenlyase subunit; High confidence in function and specificity. | pH adaption potassium efflux protein PhaD; Family membership. | 0.877 |
| hycD | sce1936 | sce4800 | sce1936 | Formate hydrogenlyase subunit; High confidence in function and specificity. | Putative NADH dehydrogenase; Family membership. | 0.615 |
| hycE | hycD | sce4797 | sce4800 | NAD-dependent dehydrogenase subunit. | Formate hydrogenlyase subunit; High confidence in function and specificity. | 0.998 |
| hycE | hycG | sce4797 | sce4796 | NAD-dependent dehydrogenase subunit. | NAD-dependent dehydrogenase subunit. | 0.999 |
| hycE | hyfB | sce4797 | sce4801 | NAD-dependent dehydrogenase subunit. | Hydrogenase-4 component B; High confidence in function and specificity. | 0.994 |
| hycE | hyfF | sce4797 | sce4798 | NAD-dependent dehydrogenase subunit. | Hydrogenase-4 component F; High confidence in function and specificity. | 0.995 |
| hycE | mnhD | sce4797 | sce1933 | NAD-dependent dehydrogenase subunit. | Putative Na(+)/H(+) antiporter subunit D; Family membership. | 0.916 |
| hycE | nuoC2 | sce4797 | sce9060 | NAD-dependent dehydrogenase subunit. | NADH dehydrogenase (ubiquinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.; Belongs to the complex I 30 kDa subunit family. | 0.641 |
| hycE | phaA | sce4797 | sce8577 | NAD-dependent dehydrogenase subunit. | pH adaptation potassium efflux protein PhaA; High confidence in function and specificity. | 0.429 |
| hycE | phaD | sce4797 | sce8579 | NAD-dependent dehydrogenase subunit. | pH adaption potassium efflux protein PhaD; Family membership. | 0.904 |
| hycE | sce1936 | sce4797 | sce1936 | NAD-dependent dehydrogenase subunit. | Putative NADH dehydrogenase; Family membership. | 0.506 |
| hycG | hycD | sce4796 | sce4800 | NAD-dependent dehydrogenase subunit. | Formate hydrogenlyase subunit; High confidence in function and specificity. | 0.999 |