Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
hycENAD-dependent dehydrogenase subunit. (495 aa)    
Predicted Functional Partners:
hycG
NAD-dependent dehydrogenase subunit.
 
 
 0.999
hycD
Formate hydrogenlyase subunit; High confidence in function and specificity.
 
 
 0.995
hyfF
Hydrogenase-4 component F; High confidence in function and specificity.
 
 0.992
hyfB
Hydrogenase-4 component B; High confidence in function and specificity.
 
 
 0.992
hycX
Hypothetical transmembrane protein, probably involved in the FHL pathway.
  
  
 0.963
mnhD
Putative Na(+)/H(+) antiporter subunit D; Family membership.
 
 
 0.864
phaD
pH adaption potassium efflux protein PhaD; Family membership.
  
 
 0.844
ureG
Urease accessory protein G; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
   
 
 0.789
sce8026
Putative NADH dehydrogenase (ubiquinone); Family membership.
 
 
 0.781
nuoI
NADH dehydrogenase I chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
 
 
 0.775
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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