Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hycDFormate hydrogenlyase subunit; High confidence in function and specificity. (307 aa)    
Predicted Functional Partners:
hycG
NAD-dependent dehydrogenase subunit.
 
 
 0.999
hycE
NAD-dependent dehydrogenase subunit.
 
 
 0.995
hyfB
Hydrogenase-4 component B; High confidence in function and specificity.
 
 
 0.993
hyfF
Hydrogenase-4 component F; High confidence in function and specificity.
 
 
 0.991
hycX
Hypothetical transmembrane protein, probably involved in the FHL pathway.
  
  
 0.920
nuoI
NADH dehydrogenase I chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.847
sce8026
Putative NADH dehydrogenase (ubiquinone); Family membership.
  
 
 0.847
mnhD
Putative Na(+)/H(+) antiporter subunit D; Family membership.
  
 
 0.831
phaD
pH adaption potassium efflux protein PhaD; Family membership.
  
 
 0.831
napG
Putative ferredoxin; Family membership.
  
 
 0.791
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
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