Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fabG83-oxoacyl-[acyl-carrier-protein] reductase; High confidence in function and specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (235 aa)    
Predicted Functional Partners:
fabZ
(3R)-hydroxymyristoyl-; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
     
 0.901
sce3356
Putative (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase.
     
 0.901
sce6685
SDR family short chain oxidoreductase; Specificity unclear; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.771
fabG3
3-oxoacyl-[acyl-carrier-protein] reductase.
  
 
   0.750
sce2893
Putative short-chain dehydrogenases; Family membership; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
   0.749
sce3451
Dehydrogenase; Family membership.
  
 
   0.721
fabH1
3-oxoacyl-[acyl-carrier-protein] synthase; High confidence in function and specificity.
   
 
  0.660
fabH2
3-oxoacyl-(acyl-carrier-protein) synthase III; Family membership.
   
 
  0.660
fabH3
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
   
 
  0.660
fabH4
3-oxoacyl-[acyl-carrier-protein] synthase; Family membership.
   
 
  0.660
Your Current Organism:
Sorangium cellulosum So ce56
NCBI taxonomy Id: 448385
Other names: S. cellulosum So ce56, Sorangium cellulosum DSM 53796, Sorangium cellulosum str. So ce56, Sorangium cellulosum strain So ce56
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.